MigVax is developing an oral COVID-19 sub-unit vaccine.
The MigVax approach utilizes a chimeric protein that presents the viral proteins to the immune system via the oropharynx.
This method, based on the IBV vaccine, generates three kinds of immunological response:
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mucosal immunity- IgA
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Blood-based immunity-IgG
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Cell-mediated immunity.
The MigVax vaccine is based on a vaccine developed for Infectious Bronchitis Virus which is a coronavirus that infects chickens.